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In a latest review, we claimed the identification along with the characterization of a completely new atypical opioid receptor with exclusive detrimental regulatory Houses towards opioid peptides.1 Our benefits showed that ACKR3/CXCR7, hitherto often known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is usually a broad-spectr